Sugi Predict

Sugi Predict / Compounds / SCHEMBL8746377

SCHEMBL8746377

SCHEMBL8746377

O=C(OC(c1ccccc1)(c1ccccc1)c1ccccc1)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNN4 O15554 4/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ HIF1A Q16665 1/20 0.45
▸ CYP1A2 P05177 2/20 0.44
▸ CYP2D6 P10635 1/20 0.42
▸ KMT2A Q03164 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ CES1 P23141 1/20 0.41
▸ KIF11 P52732 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ HDAC3 O15379 1/20 0.39
▸ HDAC4 P56524 1/20 0.39
▸ HDAC1 Q13547 1/20 0.39
▸ HDAC7 Q8WUI4 1/20 0.39
▸ HDAC2 Q92769 1/20 0.39
▸ HDAC10 Q969S8 1/20 0.39
▸ HDAC11 Q96DB2 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11003712 0.87 KCNN4 (0.39) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
SCHEMBL11003717 0.87 KCNN4 (0.53) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
Methacrylic Acid SCHEMBL27420407 0.86 KCNN4 (0.40) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
SCHEMBL14935466 0.85 KCNN4 (0.45) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
SCHEMBL2442870 0.85 KCNN4 (0.45) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
SCHEMBL4799098 0.85 ELANE (0.42) KCNN4CYP2C19HIF1ACYP1A2KMT2A
SCHEMBL7404731 0.83 KCNN4 (0.37) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
SCHEMBL7404730 0.83 KMT2A (0.37) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
SCHEMBL6399298 0.83 KCNN4 (0.43) KCNN4CYP2C19HIF1ACYP1A2CYP2D6
SCHEMBL6475358 0.81 CYP2C19 (0.42) KCNN4CYP2C19HIF1ACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469584-B1 Resist composition NIPPON PAINT CO LTD (JP) 1997-03-05 — — EP claimed
CN-117241803-A Purine nucleosides, intermediates and methods of making the same 阿斯特罗赛特制药公司 2023-12-15 — — CN disclosed
US-10207001-B2 Techniques for release of material into an environment LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2019-02-19 — — US disclosed
US-20170216437-A1 TECHNIQUES FOR RELEASE OF MATERIAL INTO AN ENVIRONMENT U.S. DEPARTMENT OF ENERGY 2017-08-03 — — US disclosed
CN-102666695-B For extruding the polycarbonate compositions of the anti-flammability with improvement of application 科思创德国股份有限公司 2016-08-17 — — CN disclosed
US-20160144030-A1 TECHNIQUES FOR RELEASE OF MATERIAL INTO AN ENVIRONMENT U.S. DEPARTMENT OF ENERGY 2016-05-26 — — US disclosed
US-20150110867-A1 TECHNIQUES FOR RELEASE OF MATERIAL INTO AN ENVIRONMENT LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2015-04-23 — — US disclosed
CN-102112523-B Modified polycarbonates with improved surface properties BAYER MATERIALSCIENCE AG 2015-04-01 — — CN disclosed
CN-102666695-A Polycarbonate compositions with improved flame retardancy for extrusion applications BAYER MATERIALSCIENCE A G 2012-09-12 — — CN disclosed
CN-102112523-A Modified polycarbonates with improved surface properties BAYER MATERIALSCIENCE AG 2011-06-29 — — CN disclosed
CN-101657498-A Products with improved flame retardancy BAYER MATERIALSCIENCE AG DE 2010-02-24 — — CN disclosed
CN-101307169-A Resin composition and resin mold FUJI XEROX CO LTD (JP) 2008-11-19 — — CN disclosed
EP-0469584-B1 Resist composition NIPPON PAINT CO LTD (JP) 1997-03-05 — — EP disclosed