Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747531 | 0.91 | NR1I2 (0.51) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL8747362 | 0.90 | NR1I2 (0.49) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL8754782 | 0.87 | NR1I2 (0.52) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL8747320 | 0.86 | NR1I2 (0.68) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL9571585 | 0.84 | NR1I2 (0.50) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL9571593 | 0.84 | NR1I2 (0.50) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL9573660 | 0.84 | NR1I2 (0.63) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL9826590 | 0.84 | NR1I2 (0.63) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL9844207 | 0.84 | NR1I2 (0.63) | NR1I2HTR2CKMT2AMAPTPPARG | |
| SCHEMBL10337520 | 0.84 | NR1I2 (0.63) | NR1I2HTR2CKMT2AMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548186-B1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES | BEECHAM GROUP PLC (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1992004353-A1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES | BEECHAM GROUP PLC (GB) | 1992-03-19 | — | — | WO | disclosed |