Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28964080 | 0.79 | TSHR (0.67) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10641630 | 0.79 | TSHR (0.67) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL18069230 | 0.79 | TSHR (0.67) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7595389 | 0.77 | TSHR (0.51) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2538613 | 0.76 | TSHR (0.63) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28836075 | 0.75 | TSHR (0.55) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2750401 | 0.75 | TSHR (0.54) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL13117667 | 0.75 | TSHR (0.54) | ESR1TSHRALDH1A1LMNATP53 | |
| SCHEMBL13117819 | 0.75 | TSHR (0.53) | ESR1TSHRALDH1A1LMNATP53 | |
| SCHEMBL18106214 | 0.74 | TSHR (0.73) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585032-B1 | Anti-ferroelectric liquid crystal and liquid crystal display device | MITSUBISHI GAS CHEMICAL CO (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5340498-A | High speed response | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0585032-A1 | Anti-ferroelectric liquid crystal and liquid crystal display device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-03-02 | — | — | EP | disclosed |