SCHEMBL8747618

SCHEMBL8747618

CCN(CCCNC(=O)OC(C)(C)C)c1ccc(N=Nc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 3/20 0.43
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.40
GAA P10253 1/20 0.39
RARB P10826 1/20 0.39
RARG P13631 1/20 0.39
BRD4 O60885 1/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
DRD2 P14416 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747614 1.00 MAPT (0.44) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL8747512 0.83 KMT2A (0.50) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL22351602 0.80 ESRRG (0.41) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL9546435 0.78 KMT2A (0.46) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL20569227 0.78 KMT2A (0.58) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL20569230 0.78 KMT2A (0.58) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL22351603 0.77 ESRRG (0.40) MAPTNPC1RAB9AKDM4ECA1
SCHEMBL18821759 0.76 KMT2A (0.59) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL18243834 0.76 KMT2A (0.67) MAPTNPC1RAB9AKDM4EKMT2A
SCHEMBL18821811 0.76 KMT2A (0.67) MAPTNPC1RAB9AKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117970589-A Optical imaging lens 浙江舜宇光学有限公司 2024-05-03 CN claimed
EP-0642669-A1 PEPTIDE SUB-LIBRARY KITS. FURKA ARPAD (HU) 1995-03-15 EP claimed
WO-1993024517-A2 PEPTIDE SUB-LIBRARY KITS FURKA ARPAD (HU) 1993-12-09 WO claimed
US-20260063630-A1 CAPTURE, PURIFICATION, AND RELEASE OF BIOLOGICAL SUBSTANCES USING A SURFACE COATING ACADEMIA SINICA (TW) 2026-03-05 US disclosed
US-12258401-B2 Anti-CD47 combination therapy TEVA PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2025-03-25 US disclosed
US-12241101-B2 Microorganism producing polyunsaturated fatty acid and method for producing polyunsaturated fatty acid KYOWA HAKKO BIO CO., LTD. (JP) 2025-03-04 US disclosed
CN-117970589-A Optical imaging lens 浙江舜宇光学有限公司 2024-05-03 CN disclosed
CN-117916270-A Epithelial cell adhesion molecule (EPCAM) inhibitors and WNT inhibitor-binding cancer treatments 周美吟 2024-04-19 CN disclosed
CN-117717604-A anti-CD 47 combination therapy 梯瓦制药澳大利亚股份有限公司 2024-03-19 CN disclosed
CN-117677397-A Epithelial cell adhesion molecule (EPCAM) inhibitors and liver growth factor receptor (HGFR) inhibitors for the treatment of cancer 周美吟 2024-03-08 CN disclosed
CN-117462668-A Methods of treating tumors with anti-PD-1 antibodies 百时美施贵宝公司 2024-01-30 CN disclosed
CN-115530636-A Heating cooker 松下知识产权经营株式会社 2022-12-30 CN disclosed
US-20220259311-A1 ANTI-CD47 COMBINATION THERAPY TEVA PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2022-08-18 US disclosed
CN-114834114-A Coating film for protecting optical member 三菱化学株式会社 2022-08-02 CN disclosed
US-20220233712-A1 EXOSOME COMPRISING STABILIZED RNA THERAPEUTICS EVOX THERAPEUTICS LTD (GB) 2022-07-28 US disclosed
EP-3965828-A1 EXOSOME COMPRISING STABILIZED RNA THERAPEUTICS Evox Therapeutics Limited (GB) 2022-03-16 EP disclosed
US-20220048962-A1 SYSTEMS AND METHODS FOR MODULATING RNA THE UNIVERSITY OF CHICAGO (US) 2022-02-17 US disclosed
EP-0642669-B1 PEPTIDE SUB-LIBRARY KITS FURKA ARPAD (HU) 1997-03-12 EP disclosed
EP-0642669-A1 PEPTIDE SUB-LIBRARY KITS. FURKA ARPAD (HU) 1995-03-15 EP disclosed
WO-1993024517-A2 PEPTIDE SUB-LIBRARY KITS FURKA ARPAD (HU) 1993-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260063630-A1 CAPTURE, PURIFICATION, AND RELEASE OF BIOLOGICAL SUBSTANCES USING A SURFACE COATING EPCAM, SELL, CD47 MAPT 1404/4885NPC1 494/4885RAB9A 2752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.