Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747751 | 0.87 | NR1H4 (0.31) | NR1H4GAAPDE2A | |
| SCHEMBL8747759 | 0.86 | NR1H4 (0.33) | NR1H4GAAPDE2ADHODH | |
| SCHEMBL8492877 | 0.85 | NR1H4 (0.33) | NR1H4DHODH | |
| SCHEMBL27456386 | 0.85 | GAA (0.33) | NR1H4GAAPDE2A | |
| SCHEMBL7924451 | 0.83 | DHODH (0.34) | GAAPDE2AMEN1KMT2ADHODH | |
| SCHEMBL8748151 | 0.83 | F2 (0.34) | GAAPDE2ADHODHKEAP1NFE2L2 | |
| SCHEMBL9115094 | 0.82 | DHODH (0.34) | GAAPDE2AMEN1KMT2ADHODH | |
| SCHEMBL8488330 | 0.82 | PDE2A (0.36) | PDE2AMEN1MAPTKMT2ADHODH | |
| SCHEMBL9116308 | 0.81 | DHODH (0.33) | PDE2AMEN1KMT2ADHODH | |
| SCHEMBL8492875 | 0.81 | DHODH (0.35) | PDE2AMEN1KMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148385-A | 4-benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-23 | — | — | CN | claimed |
| CN-1148385-A | 4-benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-23 | — | — | CN | disclosed |
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |