Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986488 | 0.86 | KMT2A (0.49) | KMT2AOPRM1HDAC4 | |
| SCHEMBL4554005 | 0.84 | PDE4A (0.47) | KMT2AOPRM1HDAC4LMNANPSR1 | |
| SCHEMBL15866986 | 0.80 | KMT2A (0.47) | KMT2AOPRM1HDAC4HSD11B1 | |
| SCHEMBL624786 | 0.80 | KMT2A (0.47) | KMT2AOPRM1HDAC4HSD11B1 | |
| SCHEMBL16691395 | 0.79 | KMT2A (0.46) | KMT2AOPRM1HDAC4HSD11B1 | |
| SCHEMBL8179858 | 0.77 | HDAC4 (0.40) | KMT2AOPRM1HDAC4LMNANPSR1 | |
| SCHEMBL13439854 | 0.76 | PIK3CD (0.45) | KMT2AOPRM1HDAC4PIK3CD | |
| SCHEMBL9248206 | 0.75 | KMT2A (0.41) | KMT2AOPRM1HDAC4LMNAPIK3CD | |
| SCHEMBL16591357 | 0.75 | KMT2A (0.68) | KMT2AOPRM1 | |
| SCHEMBL11738868 | 0.74 | KMT2A (0.42) | KMT2AOPRM1HDAC4HCAR2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |