Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.33 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082339 | 0.78 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL9187836 | 0.78 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL5082341 | 0.78 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL9189329 | 0.78 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL8747889 | 0.78 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Hydrochloric Acid SCHEMBL8896646 | 0.76 | MEN1 (0.57) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL8949610 | 0.75 | MEN1 (0.56) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL8988393 | 0.75 | MEN1 (0.56) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL8988387 | 0.75 | MEN1 (0.56) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL3677887 | 0.74 | MEN1 (0.68) | MEN1KMT2ACYP1A2HRH1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623588-B1 | Improved process for manufacturing L-(-)-carnitine from waste products having opposite configuration | SIGMA TAU IND FARMACEUTI (IT) | 1997-03-12 | — | — | EP | disclosed |
| US-5491260-A | ACYLATING CARNITINE NITRILE OR AMIDE, HYDROLYZING UNDER ACID CONDITIONS, LACTONIZING BY TREATING WITH BASE, CONVERTING TO CARNITINE BY TREATING WITH BASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1996-02-13 | — | — | US | disclosed |
| EP-0623588-A1 | Improved process for manufacturing L-(-)-carnitine from waste products having opposite configuration | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1994-11-09 | — | — | EP | disclosed |