Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.32 |
| ▸ | TACR3 | P29371 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747759 | 0.90 | NR1H4 (0.33) | DHODHNR1H4TACR3PDE2A | |
| SCHEMBL8747750 | 0.84 | DPP4 (0.35) | DHODHTACR3PDE2ATRPV1 | |
| SCHEMBL7559214 | 0.83 | DHODH (0.34) | DHODHBRAFPDE2ACRACR2A | |
| SCHEMBL8748151 | 0.82 | F2 (0.34) | DHODHPDE2A | |
| SCHEMBL8747745 | 0.81 | DHODH (0.43) | DHODHTRPV1 | |
| SCHEMBL7558771 | 0.81 | BRAF (0.33) | DHODHBRAFCRACR2ATRPV1 | |
| SCHEMBL8491101 | 0.81 | DHODH (0.37) | DHODHPDE2ACRACR2AMAPK1 | |
| SCHEMBL8747841 | 0.80 | PDE2A (0.32) | DHODHPDE2ATRPV1 | |
| SCHEMBL9115628 | 0.80 | DHODH (0.35) | DHODHNR1H4PDE2ACRACR2A | |
| SCHEMBL8747888 | 0.80 | KDM4E (0.37) | DHODHNR1H4TACR3PDE2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | claimed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | claimed |
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |