Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747894 | 1.00 | SPHK1 (0.38) | SPHK1SPHK2GAAMAPTCYP2C9 | |
| SCHEMBL8748217 | 0.99 | SPHK1 (0.36) | SPHK1SPHK2GAAMAPTCYP2C9 | |
| SCHEMBL8748020 | 0.96 | SPHK1 (0.34) | SPHK1SPHK2MAPTCYP2C9DAO | |
| SCHEMBL8747872 | 0.91 | CYP2C9 (0.39) | SPHK1MAPTCYP2C9DAO | |
| SCHEMBL8747966 | 0.88 | SPHK1 (0.39) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL8747929 | 0.88 | SPHK1 (0.39) | SPHK1SPHK2CYP2C9CYP3A4CYP2C8 | |
| SCHEMBL8448621 | 0.87 | SPHK1 (0.37) | SPHK1SPHK2GAAMAPTCYP2C9 | |
| SCHEMBL8747996 | 0.87 | SPHK1 (0.43) | SPHK1SPHK2GAAMAPT | |
| SCHEMBL8453492 | 0.87 | SPHK1 (0.37) | SPHK1SPHK2GAAMAPTCYP2C9 | |
| SCHEMBL8448617 | 0.87 | SPHK1 (0.37) | SPHK1SPHK2GAAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761799-A1 | Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device | Chisso Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |