Bromide

Bromide

SCHEMBL8748216

CCCC[n+]1ccc(-c2cc[n+](CCCC)cc2)cc1.[Br-].[Br-]

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 4/20 0.52
CHRM2 known ✓ P08172 2/20 0.52
CHRM1 known ✓ P11229 2/20 0.52
CHRM4 known ✓ P08173 1/20 0.52
CHRM5 known ✓ P08912 1/20 0.52
CHRM3 known ✓ P20309 1/20 0.52
OPRM1 known ✓ P35372 1/20 0.48
KMT2A Q03164 5/20 0.78
MEN1 O00255 4/20 0.78
MAPT P10636 3/20 0.78
TP53 P04637 1/20 0.78
CYP1A2 P05177 1/20 0.78
CYP2D6 P10635 1/20 0.78
CYP2C9 P11712 1/20 0.78
CYP2C19 P33261 1/20 0.78
HTT P42858 4/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
LMNA P02545 2/20 0.75
KDM4E B2RXH2 1/20 0.75
NPC1 O15118 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3202302 0.97 KMT2A (0.82) KMT2AMEN1MAPTTP53CYP1A2
Hydrochloric Acid SCHEMBL25240263 0.95 KMT2A (0.78) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL31567986 0.93 KMT2A (0.91) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL14656035 0.91 KMT2A (0.67) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL4077981 0.91 KMT2A (0.95) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL8364659 0.91 KMT2A (0.95) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL30020567 0.91 KMT2A (0.95) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL4076484 0.91 KMT2A (0.95) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL598489 0.91 KMT2A (0.95) KMT2AMEN1MAPTTP53CYP1A2
Bromide SCHEMBL599465 0.91 KMT2A (0.95) KMT2AMEN1MAPTTP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4933273-A ANTIFOGGING DYE, HDYRAZINE NUCLEATING AGENT EASTMAN KODAK COMPANY (US) 1990-06-12 US claimed
JP-61026041-A None JP disclosed
JP-54103794-A None JP disclosed
US-20180371310-A1 DYNAMIC RESPONSE COMPONENTS WITH AESTHETIC PROPERTIES FUNDACIÓN CIDETEC (ES) 2018-12-27 US disclosed
EP-3395927-A1 DYNAMIC RESPONSE COMPONENTS WITH AESTHETIC PROPERTIES Fundacion Cidetec (ES) 2018-10-31 EP disclosed
EP-0754966-A1 Silver halide light-sensitive photographic material and processing method thereof KONICA CORPORATION (JP) 1997-01-22 EP disclosed
US-4892812-A GRAPHIC ARTS, ROOM-LIGHT, UNSENSITIZED, MERCAPTOBENZOIC ACID MITSUBISHI PAPER MILLS, LTD. (JP) 1990-01-09 US disclosed
JP-S6126041-A SILVER HALIDE PHOTOGRAPHIC EMULSION MITSUBISHI PAPER MILLS LTD 1986-02-05 JP disclosed
US-4223082-A ELECTROMAGNETIC WAVES EASTMAN KODAK COMPANY (US) 1980-09-16 US disclosed
JP-S54103794-A IMAGE INDICATOR CANON INC 1979-08-15 JP disclosed