SCHEMBL8749015

SCHEMBL8749015

CCCC(=O)N[C@H](C(=O)C(C)=O)[C@](O)(C(C)=O)[C@@](O)(C(C)=O)[C@H](O)C(O)C(C)=O

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.31
PRSS1 P07477 1/20 0.30
CTSG P08311 1/20 0.30
CTRB1 P17538 1/20 0.30
CMA1 P23946 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749010 1.00 PSMB5 (0.31) PSMB5PRSS1CTSGCTRB1CMA1
SCHEMBL8749048 1.00 PSMB5 (0.31) PSMB5PRSS1CTSGCTRB1CMA1
SCHEMBL8748988 0.89 CYP2C9 (0.32)
SCHEMBL8748985 0.89 CYP2C9 (0.32)
SCHEMBL9663528 0.84
SCHEMBL16192197 0.82
SCHEMBL9665065 0.82
SCHEMBL27660914 0.70
SCHEMBL28066195 0.70
SCHEMBL14822814 0.65 HDAC3 (0.43) PSMB5PRSS1CTSGCTRB1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348184-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1993-03-03 EP claimed
US-5185325-A Topical for inducing hair growth; using aldono- or aldurono-monolactones as glycosaminoglycanase inhibitors; powders, shampoo, creams, lotions CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-02-09 US claimed
EP-0348184-A2 Cosmetic composition UNILEVER PLC (GB) 1989-12-27 EP claimed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
EP-0375388-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-02 EP disclosed
EP-0580409-A2 Cosmetic composition containing DOPA derivatives UNILEVER PLC (GB) 1994-01-26 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed
EP-0571198-A1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1993-11-24 EP disclosed
EP-0517371-A2 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1992-12-09 EP disclosed
EP-0490581-A1 Cosmetic composition UNILEVER PLC (GB) 1992-06-17 EP disclosed
US-5081151-A Applying a hexosaccharic acid, salt or ester CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-01-14 US disclosed
EP-0375388-A2 Cosmetic composition UNILEVER PLC (GB) 1990-06-27 EP disclosed
EP-0348184-A2 Cosmetic composition UNILEVER PLC (GB) 1989-12-27 EP disclosed