SCHEMBL8749158

SCHEMBL8749158

CCCCCCC(OC(=O)[C@@H]1CCC(=O)N1)C(=O)OCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.55
DAGLA Q9Y4D2 1/20 0.55
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.37
ALDH1A1 P00352 2/20 0.37
ACE P12821 1/20 0.36
TSHR P16473 2/20 0.36
ZDHHC7 Q9NXF8 1/20 0.34
CCR2 P41597 1/20 0.34
HDAC3 O15379 2/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC10 Q969S8 2/20 0.34
HDAC11 Q96DB2 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
POLB P06746 2/20 0.33
ALDH2 P05091 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NAAA Q02083 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749203 1.00 CNR1 (0.55) CNR1DAGLALMNAGAAALDH1A1
SCHEMBL8749222 0.99 CNR1 (0.53) CNR1DAGLALMNAGAAALDH1A1
SCHEMBL8749180 0.95 CNR1 (0.49) CNR1DAGLALMNAGAAALDH1A1
SCHEMBL8762027 0.92 CNR1 (0.54) CNR1DAGLALMNAGAATSHR
SCHEMBL8762009 0.92 CNR1 (0.54) CNR1DAGLALMNAGAATSHR
SCHEMBL8748644 0.92 CNR1 (0.54) CNR1DAGLALMNAGAATSHR
SCHEMBL7638305 0.92 CNR1 (0.54) CNR1DAGLALMNAGAATSHR
SCHEMBL8749104 0.90 CNR1 (0.46) CNR1DAGLALMNAGAAALDH1A1
SCHEMBL8749002 0.89 CNR1 (0.54) CNR1DAGLALMNAGAATSHR
SCHEMBL9511146 0.88 CNR1 (0.57) CNR1DAGLALMNAGAACCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0277428-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-23 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
EP-0342055-A2 Use of pyroglutamic acid alkyl esters for the manufacture of a medicament for the treatment of ichthyosis UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342054-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0342056-A2 Cosmetic composition UNILEVER PLC (GB) 1989-11-15 EP claimed
EP-0176217-B1 PYROGLUTAMIC ACID ESTERS, THEIR SYNTHESIS AND USE IN TOPICAL PRODUCTS UNILEVER PLC (GB) 1989-06-07 EP claimed
US-4774255-A SKIN DISORDERS LEVER BROTHERS COMPANY (US) 1988-09-27 US claimed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP claimed
EP-0446047-B1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1997-06-11 EP disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0334586-A1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0334585-A2 Cosmetic composition UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0176217-B1 PYROGLUTAMIC ACID ESTERS, THEIR SYNTHESIS AND USE IN TOPICAL PRODUCTS UNILEVER PLC (GB) 1989-06-07 EP disclosed
US-4832946-A CELL CULTURE FOR HAIR GROWTH CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC., A CORP. OF NY 1989-05-23 US disclosed
EP-0277428-A2 Cosmetic composition UNILEVER PLC (GB) 1988-08-10 EP disclosed
EP-0272920-A1 Cosmetic composition UNILEVER PLC (GB) 1988-06-29 EP disclosed