SCHEMBL8749306

SCHEMBL8749306

CC#CO[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057565 0.64
SCHEMBL131923 0.64
SCHEMBL14477548 0.61
SCHEMBL4507474 0.58
SCHEMBL5968783 0.58
SCHEMBL4507479 0.58
SCHEMBL69353 0.58
SCHEMBL3267509 0.58
SCHEMBL9721257 0.56
Hydrochloric Acid SCHEMBL20996517 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510562-B Synthesis method of medical intermediate 2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-04-26 CN claimed
CN-117551155-B Synthesis method of 5'-O-DMT-2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-03-29 CN claimed
CN-117551155-A Synthesis method of 5'-O-DMT-2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-02-13 CN claimed
CN-117510562-A Synthesis method of medical intermediate 2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-02-06 CN claimed
US-12637568-B2 Curable hot-melt silicone composition, cured product thereof, and laminate including curable hot-melt silicone composition or cured product thereof DOW TORAY CO., LTD. (JP) 2026-05-26 US disclosed
CN-117510562-B Synthesis method of medical intermediate 2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-04-26 CN disclosed
CN-117510562-B Synthesis method of medical intermediate 2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-04-26 CN disclosed
CN-117551155-B Synthesis method of 5'-O-DMT-2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-03-29 CN disclosed
CN-117551155-A Synthesis method of 5'-O-DMT-2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-02-13 CN disclosed
CN-117510562-A Synthesis method of medical intermediate 2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-02-06 CN disclosed
CN-117510562-A Synthesis method of medical intermediate 2' -O-propynyl-uridine 苏州诺维康生物科技有限公司 2024-02-06 CN disclosed
US-20230151215-A1 CURABLE HOT-MELT SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND LAMINATE INCLUDING CURABLE HOT-MELT SILICONE COMPOSITION OR CURED PRODUCT THEREOF DOW TORAY CO., LTD. (JP) 2023-05-18 US disclosed
EP-0459381-B1 Process for the preparation of 10-(2-propynyl)ester-4-ene-3,17-dione MERRELL PHARMA INC (US) 1997-03-19 EP disclosed
US-5516922-A Process for the preparation of 10(2-propynyl)estr-4-ene-3,17-dione MERRELL PHARMACEUTICALS INC. (US) 1996-05-14 US disclosed
EP-0459381-A2 Process for the preparation of 10-(2-propynyl)ester-4-ene-3,17-dione MERRELL PHARMACEUTICALS INC. (US) 1991-12-04 EP disclosed