Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156734 | 1.00 | HTR2C (0.51) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1568880 | 0.90 | HTR2C (0.49) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1568877 | 0.90 | HTR2C (0.49) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1568630 | 0.88 | HTR2C (0.47) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1568627 | 0.88 | HTR2C (0.47) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL26782488 | 0.88 | HTR2C (0.47) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1568398 | 0.87 | HTR2C (0.48) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1568401 | 0.87 | HTR2C (0.48) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7406225 | 0.86 | HTT (0.47) | HTR2CALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7406222 | 0.86 | HTT (0.47) | HTR2CALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482080-B1 | SMALL CYCLIC PLATELET AGGREGATION INHIBITORS | GENENTECH INC (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0493506-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1992-07-08 | — | — | EP | disclosed |
| WO-1991004247-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1991-04-04 | — | — | WO | disclosed |