⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966333 | 0.70 | — | — | |
| SCHEMBL17850030 | 0.67 | — | — | |
| SCHEMBL19018621 | 0.67 | — | — | |
| SCHEMBL19751002 | 0.63 | — | — | |
| SCHEMBL10945078 | 0.60 | — | — | |
| SCHEMBL10339205 | 0.56 | — | — | |
| SCHEMBL10356513 | 0.56 | — | — | |
| SCHEMBL2313972 | 0.56 | — | — | |
| SCHEMBL22675788 | 0.53 | — | — | |
| Ethane SCHEMBL28662632 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214994-A1 | (3-FLUORO-2-HYDROXY)PROPYL-FUNCTIONALIZED ARYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR THE DIAGNOSIS OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASES | FUTURECHEM CO., LTD. (KR) | 2012-08-23 | — | — | US | claimed |
| WO-2010006954-A1 | NOVEL N-SUBSTITUTED BETA-AMINO ACID ESTERS | DSM IP ASSETS B.V. (NL) | 2010-01-21 | — | — | WO | claimed |
| CN-110650954-B | anticancer compounds | 法马马有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-111848369-B | Eribulin intermediate and synthesis method and application thereof | 北京天一绿甫医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-114344186-A | Pigment stabilizer | C·扎维拉 | 2022-04-15 | — | — | CN | disclosed |
| CN-109362222-B | Selective estrogen receptor degradants and uses thereof | 益方生物科技(上海)股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-111848369-A | Eribulin intermediate, and synthesis method and application thereof | 北京天一绿甫医药科技有限公司 | 2020-10-30 | — | — | CN | disclosed |
| EP-3704130-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | Melinta Therapeutics, Inc. (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3140310-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | Rempex Pharmaceuticals, Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-3083630-A1 | PROCESS METHODS FOR PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Calistoga LLC (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015171430-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | WO | disclosed |
| US-20050053748-A1 | METAL SALT ACTIVATORS FOR USE IN LEUCO DYE COMPOSITIONS | HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. | 2005-03-10 | — | — | US | disclosed |
| US-6852895-B2 | Oxidation of a phenol compound | ZYMES, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-0966479-A4 | POLYPROLYL INHIBITORS OF CYCLOPHILIN | GUILFORD PHARM INC (US) | 2004-12-08 | — | — | EP | disclosed |
| EP-1328654-A1 | A PRACTICAL, COST-EFFECTIVE SYNTHESIS OF COQ10 | The Regents of the University of California (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20030073869-A1 | Practical, cost-effective synthesis of CoQ10 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-04-17 | — | — | US | disclosed |
| US-6545184-B1 | Electron transfer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-08 | — | — | US | disclosed |
| WO-2002014530-A1 | A PRACTICAL, COST-EFFECTIVE SYNTHESIS OF COQ10 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-02-21 | — | — | WO | disclosed |
| EP-0966479-A1 | POLYPROLYL INHIBITORS OF CYCLOPHILIN | GUILFORD PHARMACEUTICALS INC. (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998025950-A1 | POLYPROLYL INHIBITORS OF CYCLOPHILIN | GUILFORD PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |