Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944793 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL27762277 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL29556814 | 0.97 | TSHR (0.40) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31508932 | 0.92 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31509527 | 0.92 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31509341 | 0.92 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11533275 | 0.92 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31508881 | 0.92 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL6861326 | 0.92 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31508789 | 0.92 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758346-A1 | PROCESS FOR THE PREPARATION OF AN ELASTOMERIC POLYMER FROM ETHYLENE, ALPHA-OLEFIN AND OPTIONALLY DIENE | DSM N.V. (NL) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030698-A1 | PROCESS FOR THE PREPARATION OF AN ELASTOMERIC POLYMER FROM ETHYLENE, ALPHA-OLEFIN AND OPTIONALLY DIENE | DSM N.V. (NL) | 1995-11-16 | — | — | WO | disclosed |