Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045160 | 0.88 | NPSR1 (0.61) | NPSR1HDAC8F10PTPN1PREP | |
| SCHEMBL7627035 | 0.83 | PRCP (0.67) | NPSR1PREPPRCPSMN1; SMN2 | |
| SCHEMBL8750726 | 0.83 | PRCP (0.64) | NPSR1PREPPRCPSMN1; SMN2 | |
| SCHEMBL1061148 | 0.77 | NPSR1 (0.60) | NPSR1HDAC8F10PTPN1PREP | |
| SCHEMBL9572243 | 0.76 | NPSR1 (0.64) | NPSR1HDAC8F10PTPN1 | |
| SCHEMBL9572242 | 0.76 | NPSR1 (0.64) | NPSR1HDAC8F10PTPN1 | |
| SCHEMBL1049445 | 0.76 | NPSR1 (0.63) | NPSR1HDAC8F10PTPN1PREP | |
| SCHEMBL1052393 | 0.75 | NPSR1 (0.62) | NPSR1F10PTPN1ABCB11ACE | |
| SCHEMBL14862925 | 0.75 | NPSR1 (0.62) | NPSR1F10PTPN1ABCB11ACE | |
| SCHEMBL3629346 | 0.75 | NPSR1 (0.62) | NPSR1F10PTPN1ABCB11ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764151-A2 | PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034538-A2 | PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1995-12-21 | — | — | WO | disclosed |