Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.68 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750947 | 1.00 | PREP (0.68) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL8750859 | 1.00 | PREP (0.68) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL488745 | 0.97 | PREP (0.68) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL6384850 | 0.97 | PREP (0.68) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL488744 | 0.97 | PREP (0.68) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL8161156 | 0.96 | PREP (0.67) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL8161155 | 0.96 | PREP (0.67) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL8161153 | 0.96 | PREP (0.67) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL11262909 | 0.96 | PREP (0.69) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL11262912 | 0.96 | PREP (0.69) | PREPCTRB1NPSR1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764151-A2 | PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034538-A2 | PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1995-12-21 | — | — | WO | disclosed |