SCHEMBL8750965

SCHEMBL8750965

CCCCCCCCc1cnc(-c2ccc(OCC(F)CCCCC)cc2)nc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.53
RAB9A P51151 7/20 0.50
SMN1; SMN2 Q16637 6/20 0.50
MAPT P10636 5/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 2/20 0.50
USP2 O75604 2/20 0.50
ALDH1A1 P00352 2/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
NPC1 O15118 5/20 0.46
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
S1PR1 P21453 3/20 0.42
S1PR4 O95977 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9346251 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL7752863 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL7062161 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL7062159 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL8021050 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL9367202 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL9346266 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL9345635 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL13028999 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL9345629 1.00 RARB (0.53) RARBRAB9ASMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460624-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1997-09-10 EP disclosed
EP-0440136-B1 Liquid crystal composition and liquid crystal device containing the same CANON KK (JP) 1997-04-02 EP disclosed
US-5599479-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1997-02-04 US disclosed
EP-0499252-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1996-09-11 EP disclosed
US-5501818-A PYRIMIDINE COMPOUNDS, IMPROVED RESPONSE SPEED WITH LESS TEMPERATURE DEPENDENCE CANON KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
EP-0401522-B1 Liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-12-06 EP disclosed
EP-0499222-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-05-03 EP disclosed
EP-0500072-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-05-03 EP disclosed
US-5391318-A Liquid crystal composition and liquid crystal device containing the same CANON KABUSHIKI KAISHA (JP) 1995-02-21 US disclosed
EP-0347944-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-02-01 EP disclosed
EP-0401522-A1 Liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-12-12 EP disclosed
EP-0355374-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-02-28 EP disclosed
EP-0355313-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-02-28 EP disclosed
EP-0352479-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed
EP-0347942-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0347940-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0347944-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
US-4867903-A FERROELECTRIC LIQUID CRYSTALS CANON KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
US-4851461-A PHOTOSTABILIZERS ICI AMERICAS INC. (US) 1989-07-25 US disclosed
EP-0237007-A2 Fluoroalkane derivative and liquid crystal composition CANON KABUSHIKI KAISHA (JP) 1987-09-16 EP disclosed