Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752081 | 0.81 | ESR1 (0.58) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL243995 | 0.79 | TSHR (0.71) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL7591679 | 0.78 | ESR1 (0.55) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL11418643 | 0.75 | TSHR (0.77) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL3665345 | 0.75 | ESR1 (0.69) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL21705266 | 0.75 | ESR1 (0.46) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4628086 | 0.74 | TSHR (0.65) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4626773 | 0.74 | TSHR (0.65) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4627375 | 0.74 | TSHR (0.65) | ESR1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL28451057 | 0.74 | TSHR (0.65) | ESR1TSHRTDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566690-B1 | TORQUE RESISTANT TUBING | COHEN SOLOMON (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0566690-A4 | TORQUE RESISTANT TUBING. | FLYNN VINCENT J (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0566690-A1 | TORQUE RESISTANT TUBING. | FLYNN VINCENT J (US) | 1993-10-27 | — | — | EP | disclosed |
| WO-1993008861-A1 | TORQUE RESISTANT TUBING | FLYNN VINCENT J (US) | 1993-05-13 | — | — | WO | disclosed |
| US-5085649-A | Torque controlled tubing | COHEN, MARK | 1992-02-04 | — | — | US | disclosed |