⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1669047 | 0.78 | — | — | |
| SCHEMBL7281609 | 0.74 | — | — | |
| SCHEMBL5621329 | 0.69 | — | — | |
| SCHEMBL11915555 | 0.65 | — | — | |
| SCHEMBL18022119 | 0.65 | — | — | |
| SCHEMBL8675157 | 0.65 | — | — | |
| SCHEMBL30886961 | 0.65 | — | — | |
| SCHEMBL383691 | 0.65 | — | — | |
| SCHEMBL7077764 | 0.65 | — | — | |
| SCHEMBL1457003 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | claimed |
| US-6127576-A | Aminophenyl ketone derivatives and a method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 2000-10-03 | — | — | US | claimed |
| EP-0849262-A1 | Aminophenyl ketone derivatives and a method for the preparation thereof | American Cyanamid Company (US) | 1998-06-24 | — | — | EP | claimed |
| JP-10226676-A | — | — | None | — | — | JP | disclosed |
| US-9624200-B2 | Therapeutic piperazines | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2017-04-18 | — | — | US | disclosed |
| US-20150087645-A1 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. | 2015-03-26 | — | — | US | disclosed |
| US-8927546-B2 | Therapeutic piperazines | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2015-01-06 | — | — | US | disclosed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | disclosed |
| US-6127576-A | Aminophenyl ketone derivatives and a method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| JP-H10226676-A | AMINOPHENYL KETONE DERIVATIVE AND ITS PRODUCTION | AMERICAN CYANAMID CO | 1998-08-25 | — | — | JP | disclosed |
| EP-0849262-A1 | Aminophenyl ketone derivatives and a method for the preparation thereof | American Cyanamid Company (US) | 1998-06-24 | — | — | EP | disclosed |