⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28375942 | 0.76 | — | — | |
| SCHEMBL11038493 | 0.74 | — | — | |
| SCHEMBL22770694 | 0.72 | — | — | |
| SCHEMBL25948767 | 0.72 | — | — | |
| SCHEMBL7164470 | 0.72 | — | — | |
| SCHEMBL875297 | 0.72 | — | — | |
| SCHEMBL2993121 | 0.72 | — | — | |
| SCHEMBL3628855 | 0.72 | — | — | |
| SCHEMBL28442260 | 0.72 | — | — | |
| SCHEMBL434318 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |
| EP-3753937-B1 | ATR INHIBITOR AND APPLICATION THEREOF | WUXI BIOCITY BIOPHARMACEUTICS CO LTD (CN) | 2024-01-10 | — | — | EP | disclosed |
| CN-111971285-B | Imidazopyrrolidone compound and application thereof | 罗欣药业(上海)有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111712499-B | ATR inhibitor and application thereof | 无锡智康弘义生物科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-11639355-B2 | Substituted pyrrolo[3,4-d]imidazoles as MDM2-p53 inhibitors | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2023-05-02 | — | — | US | disclosed |
| CN-111465598-B | Glucoside derivative as SGLTs inhibitor and application thereof | 山东丹红制药有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20230117695-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-04-20 | — | — | US | disclosed |
| EP-3738956-B1 | CXCR2 ANTAGONIST | SHENZHEN OPTIMUM BIOLOGICAL TECH CO LTD (CN) | 2023-03-01 | — | — | EP | disclosed |
| EP-3712147-B1 | SGLTS INHIBITOR AND APPLICATION THEREOF | SHANGDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2023-01-25 | — | — | EP | disclosed |
| US-20090062348-A1 | Antifungal Agent Containing Pyridine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1864980-A1 | ANTIFUNGAL AGENT CONTAINING PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1669348-A1 | NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND | Eisai Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1165828-A4 | 50 HUMAN SECRETED PROTEINS | HUMAN GENOME SCIENCES INC (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1165828-A1 | 50 HUMAN SECRETED PROTEINS | Human Genome Sciences, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058496-A1 | 50 HUMAN SECRETED PROTEINS | HUMAN GENOME SCIENCES, INC. (US) | 2000-10-05 | — | — | WO | disclosed |
| EP-0796259-A2 | NOVEL PYRIMIDINYLOXY- AND PYRIMIDINYLAMINO-ETHYLPHENYL-DIOXOLANE DERIVATIVES | Novartis AG (CH) | 1997-09-24 | — | — | EP | disclosed |
| WO-1997009316-A1 | 4-[2-(PYRIMIDIN-4-OXY- OR 4-YLAMINO)-ETHYL]-PHENYL-OXIMES | NOVARTIS AG (CH) | 1997-03-13 | — | — | WO | disclosed |
| WO-1996017843-A2 | NOVEL PYRIMIDINYLOXY- AND PYRIMIDINYLAMINO-ETHYLPHENYL-DIOXOLANE DERIVATIVES | NOVARTIS AG (CH) | 1996-06-13 | — | — | WO | disclosed |