SCHEMBL8754397

SCHEMBL8754397

OC1CCCCC1(O)c1ccccc1.O[C@H]1CCCC[C@@H]1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 5/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
OPRM1 P35372 4/20 0.37
OPRL1 P41146 3/20 0.37
SLC6A9 P48067 3/20 0.37
SLC6A5 Q9Y345 3/20 0.37
TSHR P16473 3/20 0.36
CYP2D6 P10635 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
ALDH1A1 P00352 1/20 0.35
APEX1 P27695 1/20 0.35
BLM P54132 1/20 0.35
CNR2 P34972 2/20 0.35
NPY1R P25929 1/20 0.35
HTT P42858 1/20 0.35
NPY2R P49146 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1852711 0.86 CNR2 (0.42) OPRM1OPRL1SLC6A9SLC6A5CNR2
SCHEMBL7905480 0.86 CNR2 (0.42) OPRM1OPRL1SLC6A9SLC6A5CNR2
SCHEMBL7911972 0.86 CNR2 (0.42) OPRM1OPRL1SLC6A9SLC6A5CNR2
SCHEMBL6933056 0.86 CNR2 (0.42) OPRM1OPRL1SLC6A9SLC6A5CNR2
SCHEMBL6543483 0.86 CNR2 (0.42) OPRM1OPRL1SLC6A9SLC6A5CNR2
SCHEMBL7911980 0.86 CNR2 (0.42) OPRM1OPRL1SLC6A9SLC6A5CNR2
SCHEMBL11400432 0.85 CNR2 (0.41) OPRM1OPRL1SLC6A9SLC6A5CNR2
SCHEMBL1866342 0.81 CNR2 (0.40) OPRL1CNR2NPY1RHTTNPY2R
SCHEMBL407263 0.79 SLC18A3 (0.59) SLC18A3MEN1KMT2ATSHRCYP2D6
SCHEMBL3869911 0.79 SLC18A3 (0.59) SLC18A3MEN1KMT2ATSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759021-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 2-ARYLCYCLOHEXANOLS HOECHST CELANESE CORPORATION (US) 1997-02-26 EP disclosed
WO-1995031424-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 2-ARYLCYCLOHEXANOLS HOECHST CELANESE CORPORATION (US) 1995-11-23 WO disclosed