SCHEMBL8758409

SCHEMBL8758409

O=C(O)CCCCc1ccc2c(c1)CC(CNS(=O)(=O)c1ccc(Cl)cc1)C2

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 16/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8758625 0.99 TBXA2R (0.81) TBXA2R
SCHEMBL8757098 0.97 TBXA2R (0.83) TBXA2R
SCHEMBL8757930 0.93 TBXA2R (0.82) TBXA2R
SCHEMBL5673556 0.86 TBXA2R (0.85) TBXA2R
SCHEMBL8982196 0.85 TBXA2R (0.77) TBXA2R
SCHEMBL8758383 0.85 TBXA2R (0.70) TBXA2R
SCHEMBL8758402 0.84 TBXA2R (0.63) TBXA2R
SCHEMBL8757797 0.83 TBXA2R (0.70) TBXA2R
SCHEMBL8757119 0.83 TBXA2R (0.74) TBXA2R
SCHEMBL10405618 0.83 TBXA2R (0.69) TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0773019-A1 HYPERLIPEMIA REMEDY ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-05-14 EP disclosed
EP-0589037-B1 INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME ZERIA PHARM CO LTD (JP) 1996-05-29 EP disclosed
US-5409956-A A sulfonylaminoalkylindan carboxylic acid or ester for treating thrombosis, vasospasm or asthma ZERIA PHARMACEUTICAL CO., LTD. (JP) 1995-04-25 US disclosed
EP-0589037-A1 INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1994-03-30 EP disclosed