Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethachlor SCHEMBL8540169 | 0.87 | TP53 (0.53) | TP53KMT2AMEN1ALDH1A1NR1I2 | |
| Dimethachlor SCHEMBL67002 | 0.87 | TP53 (0.53) | TP53KMT2AMEN1ALDH1A1NR1I2 | |
| Dimethachlor SCHEMBL22534179 | 0.83 | NR1I2 (0.56) | TP53KMT2AMEN1ALDH1A1NR1I2 | |
| SCHEMBL9212997 | 0.80 | TP53 (0.50) | TP53KMT2AMEN1ALDH1A1NR1I2 | |
| SCHEMBL9208363 | 0.79 | TP53 (0.49) | TP53KMT2AMEN1ALDH1A1NR1I2 | |
| SCHEMBL9210625 | 0.78 | TP53 (0.68) | TP53KMT2AMEN1HSD17B10ALDH1A1 | |
| Acetochlor SCHEMBL10481232 | 0.77 | TP53 (0.77) | TP53KMT2AMEN1NAPRTHSD17B10 | |
| Dimethachlor SCHEMBL18115249 | 0.77 | TP53 (0.41) | TP53KMT2AMEN1ALDH1A1NR1I2 | |
| Dimethachlor SCHEMBL18115298 | 0.77 | NR1I2 (0.47) | TP53KMT2AMEN1ALDH1A1NR1I2 | |
| SCHEMBL10626969 | 0.76 | TP53 (0.49) | TP53KMT2AMEN1ALDH1A1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772395-A1 | SPHERICAL MICROPARTICLES HAVING AN INNER WAX COATING DEPOSITED AROUND BIOLOGICALLY ACTIVE COMPOUNDS | Novartis AG (CH) | 1997-05-14 | — | — | EP | disclosed |
| EP-0772394-A1 | PROCESS FOR THE PREPARATION OF SPHERICAL MICROPARTICLES CONTAINING BIOLOGICALLY ACTIVE COMPOUNDS | Novartis AG (CH) | 1997-05-14 | — | — | EP | disclosed |
| EP-0772393-A1 | SPHERICAL MICROPARTICLES COMPRISING A NUCLEATION PROMOTER AND BIOLOGICALLY ACTIVE COMPOUNDS | Novartis AG (CH) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003041-A1 | SPHERICAL MICROPARTICLES HAVING AN INNER WAX COATING DEPOSITED AROUND BIOLOGICALLY ACTIVE COMPOUNDS | CIBA-GEIGY AG (CH) | 1996-02-08 | — | — | WO | disclosed |
| WO-1996003040-A1 | PROCESS FOR THE PREPARATION OF SPHERICAL MICROPARTICLES CONTAINING BIOLOGICALLY ACTIVE COMPOUNDS | CIBA-GEIGY AG (CH) | 1996-02-08 | — | — | WO | disclosed |
| WO-1996003039-A1 | SPHERICAL MICROPARTICLES COMPRISING A NUCLEATION PROMOTER AND BIOLOGICALLY ACTIVE COMPOUNDS | CIBA-GEIGY AG (CH) | 1996-02-08 | — | — | WO | disclosed |