Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876046 | 1.00 | PDK2 (0.33) | PDK2ORAI1 | |
| SCHEMBL876045 | 1.00 | PDK2 (0.33) | PDK2ORAI1 | |
| SCHEMBL883516 | 0.95 | POLB (0.31) | PDK2 | |
| SCHEMBL12503961 | 0.95 | POLB (0.31) | PDK2 | |
| SCHEMBL12503962 | 0.95 | POLB (0.31) | PDK2 | |
| SCHEMBL10072316 | 0.95 | PDK2 (0.31) | PDK2ORAI1 | |
| SCHEMBL883513 | 0.93 | PDK2 (0.31) | PDK2ORAI1 | |
| SCHEMBL10072319 | 0.93 | PDK2 (0.32) | PDK2ORAI1 | |
| SCHEMBL12503972 | 0.92 | ACACB (0.32) | PDK2ORAI1 | |
| SCHEMBL12503970 | 0.92 | ACACB (0.32) | PDK2ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619189-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038851-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-03-29 | — | — | WO | claimed |
| EP-2619189-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038851-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-03-29 | — | — | WO | disclosed |