Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759863 | 0.93 | NR1I2 (0.47) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL3092233 | 0.84 | NR1I2 (0.47) | ALDH1A1NR1I2 | |
| SCHEMBL17423122 | 0.84 | NR1I2 (0.47) | ALDH1A1NR1I2 | |
| SCHEMBL6679763 | 0.84 | NR1I2 (0.47) | ALDH1A1NR1I2 | |
| SCHEMBL6683946 | 0.84 | NR1I2 (0.47) | ALDH1A1NR1I2 | |
| SCHEMBL10863122 | 0.84 | NR1I2 (0.47) | ALDH1A1NR1I2 | |
| Hydrogen Sulfide SCHEMBL28214441 | 0.83 | NR1I2 (0.46) | ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23849703 | 0.82 | NR1I2 (0.49) | NR1I2 | |
| SCHEMBL21633712 | 0.82 | NR1I2 (0.49) | NR1I2 | |
| SCHEMBL21633771 | 0.82 | NR1I2 (0.49) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674615-B1 | DECOLORIZATION OF ALKYLATED DIARYLAMINES | GOODRICH CO B F (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0674615-A1 | DECOLORIZATION OF ALKYLATED DIARYLAMINES. | GOODRICH CO B F (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014753-A1 | DECOLORIZATION OF ALKYLATED DIARYLAMINES | THE B.F. GOODRICH COMPANY (US) | 1994-07-07 | — | — | WO | disclosed |
| US-5321159-A | Decolorization of alkylated diarylamines | THE B. F. GOODRICH COMPANY (US) | 1994-06-14 | — | — | US | disclosed |