Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760934 | 0.89 | UPP1 (0.37) | UPP1ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL8760050 | 0.86 | UPP1 (0.35) | UPP1PNP | |
| Hept SCHEMBL384288 | 0.85 | UPP1 (0.48) | UPP1ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL9354034 | 0.84 | UPP1 (0.46) | UPP1ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL9353985 | 0.84 | UPP1 (0.49) | UPP1ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL8760090 | 0.83 | UPP1 (0.49) | UPP1ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL9353745 | 0.83 | UPP1 (0.48) | UPP1ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL9357336 | 0.81 | UPP1 (0.58) | UPP1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8760742 | 0.81 | UPP1 (0.48) | UPP1ALDH1A1POLBHPGDPNP | |
| SCHEMBL9354063 | 0.81 | UPP1 (0.44) | UPP1ALDH1A1TSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | claimed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | claimed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | claimed |
| JP-3284624-A | — | — | None | — | — | JP | disclosed |
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| JP-H03284624-A | ANTIVIRAL AGENT | MITSUBISHI KASEI CORP | 1991-12-16 | — | — | JP | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |