Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763462 | 1.00 | SCN9A (0.45) | SCN9AHPGDPPOXNPSR1PDE4D | |
| SCHEMBL8762338 | 0.99 | SCN9A (0.43) | SCN9AHPGDPPOXNPSR1PDE4D | |
| SCHEMBL8763572 | 0.88 | NPSR1 (0.51) | SCN9ANPSR1PDE4DPDE4APDE4B | |
| SCHEMBL8763496 | 0.85 | NPC1 (0.51) | SCN9AHPGDPPOXNPSR1PDE4D | |
| SCHEMBL8760718 | 0.85 | SCN9A (0.46) | SCN9APPOXNPSR1PDE4DPDE4A | |
| SCHEMBL9068391 | 0.85 | SCN9A (0.48) | SCN9APPOXNPSR1PDE4DPDE4A | |
| SCHEMBL8761735 | 0.84 | SCN9A (0.47) | SCN9APPOXNPSR1PDE4DPDE4A | |
| SCHEMBL8760706 | 0.83 | SCN9A (0.40) | SCN9AHPGDPPOXPDE4DPDE4A | |
| SCHEMBL8760792 | 0.82 | SCN9A (0.46) | SCN9APPOXNPSR1PDE4DPDE4A | |
| SCHEMBL11032694 | 0.82 | DHODH (0.43) | HPGDPPOXNPSR1DHODHACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635485-B1 | TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5554581-A | Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| US-5506190-A | Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-04-09 | — | — | US | disclosed |