Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762681 | 1.00 | SRD5A2 (0.49) | SRD5A2ARSRD5A1 | |
| SCHEMBL14387399 | 0.88 | SRD5A2 (0.48) | SRD5A2ARSRD5A1 | |
| SCHEMBL14355664 | 0.88 | SRD5A2 (0.48) | SRD5A2ARSRD5A1 | |
| SCHEMBL14355643 | 0.88 | SRD5A2 (0.48) | SRD5A2ARSRD5A1 | |
| SCHEMBL8761601 | 0.88 | SRD5A2 (0.48) | SRD5A2ARSRD5A1 | |
| SCHEMBL14477871 | 0.88 | SRD5A2 (0.48) | SRD5A2ARSRD5A1 | |
| SCHEMBL8761603 | 0.88 | SRD5A2 (0.48) | SRD5A2ARSRD5A1 | |
| SCHEMBL14387333 | 0.88 | SRD5A2 (0.48) | SRD5A2ARSRD5A1 | |
| SCHEMBL5841810 | 0.85 | SRD5A2 (0.62) | SRD5A2ARSRD5A1 | |
| SCHEMBL5841808 | 0.85 | SRD5A2 (0.62) | SRD5A2ARSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013001322-A1 | PROCESS FOR THE SYNTHESIS OF (5α,17β)-N-[(2,5-BIS(TRIFLUOROMETHYL)-PHENYL]-3-OXO-4-AZA-5-ANDROST-1-ENE-17-CARBOXAMIDE | RICHTER GEDEON NYRT. (HU) | 2013-01-03 | — | — | WO | disclosed |
| WO-2013001322-A1 | PROCESS FOR THE SYNTHESIS OF (5α,17β)-N-[(2,5-BIS(TRIFLUOROMETHYL)-PHENYL]-3-OXO-4-AZA-5-ANDROST-1-ENE-17-CARBOXAMIDE | RICHTER GEDEON NYRT. (HU) | 2013-01-03 | — | — | WO | disclosed |
| EP-0473225-B1 | Process for iodinating or brominating the alpha-methylenic carbon of a 3-oxo-4aza-steroid | MERCK & CO INC (US) | 1997-07-09 | — | — | EP | disclosed |