Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | P4HB | P07237 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 8/20 | 0.53 |
| ▸ | CA9 | Q16790 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PON1 | P27169 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15104539 | 0.99 | KDM4E (0.63) | KDM4EALDH1A1GLAHPGDMAOB | |
| SCHEMBL15104536 | 0.88 | KDM4E (0.60) | KDM4EALDH1A1GLAHPGDMAOB | |
| SCHEMBL876286 | 0.81 | MCL1 (0.73) | KDM4EALDH1A1GLAHPGDMAOB | |
| SCHEMBL15984890 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1GLAHPGDMAOB | |
| SCHEMBL7000517 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1GLAHPGDMAOB | |
| SCHEMBL5345045 | 0.77 | MAOB (0.77) | KDM4EALDH1A1GLAHPGDMAOB | |
| SCHEMBL18074001 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1GLAHPGDMAOB | |
| Hydrazine SCHEMBL28219088 | 0.76 | ESR1 (0.60) | KDM4EALDH1A1GLAHPGDMAOB | |
| SCHEMBL4187220 | 0.76 | MAOB (1.00) | KDM4EALDH1A1GLAHPGDMAOB | |
| B-D-Galactose SCHEMBL15104533 | 0.75 | KMT2A (0.52) | KDM4EALDH1A1GLAHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3196274-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, AND USES THEREOF | Etablissements J. Soufflet (FR) | 2017-07-26 | — | — | EP | claimed |
| EP-2619281-B1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | J SOUFFLET ETS (FR) | 2016-11-09 | — | — | EP | claimed |
| EP-2619281-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | ETS J. Soufflet (FR) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038614-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | ETS J. SOUFFLET (FR) | 2012-03-29 | — | — | WO | claimed |
| EP-3196274-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, AND USES THEREOF | Etablissements J. Soufflet (FR) | 2017-07-26 | — | — | EP | disclosed |
| EP-3196274-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, AND USES THEREOF | Etablissements J. Soufflet (FR) | 2017-07-26 | — | — | EP | disclosed |
| EP-2619281-B1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | J SOUFFLET ETS (FR) | 2016-11-09 | — | — | EP | disclosed |
| US-20140234884-A1 | FLUOROGENIC SUBSTRATES, METHODS OF MAKING THE SUBSTRATES, AND METHODS OF DETECTING GLYCOSIDASE ACTIVITIES | UNIVERSITE DE STRASBOURG (FR) | 2014-08-21 | — | — | US | disclosed |
| US-20140234884-A1 | FLUOROGENIC SUBSTRATES, METHODS OF MAKING THE SUBSTRATES, AND METHODS OF DETECTING GLYCOSIDASE ACTIVITIES | UNIVERSITE DE STRASBOURG (FR) | 2014-08-21 | — | — | US | disclosed |
| US-8716496-B2 | Sulfonated coumarins, their synthesis, fluorogenic substrates resulting from grafting of these coumarins on sugars, method for obtaining these substrates, and their applications | Soufflet, Ets J. (FR) | 2014-05-06 | — | — | US | disclosed |
| US-8716496-B2 | Sulfonated coumarins, their synthesis, fluorogenic substrates resulting from grafting of these coumarins on sugars, method for obtaining these substrates, and their applications | Soufflet, Ets J. (FR) | 2014-05-06 | — | — | US | disclosed |
| EP-2619281-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | ETS J. Soufflet (FR) | 2013-07-31 | — | — | EP | disclosed |
| US-20130183700-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2013-07-18 | — | — | US | disclosed |
| US-20130183700-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2013-07-18 | — | — | US | disclosed |
| WO-2012038614-A1 | SULFONATED COUMARINS, SYNTHESIS THEREOF, FLUOROGENIC SUBSTRATES RESULTING FROM GRAFTING SAID COUMARINS ONTO SUGARS, METHOD FOR PREPARING SAID SUBSTRATES, AND USES THEREOF | ETS J. SOUFFLET (FR) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234884-A1 | FLUOROGENIC SUBSTRATES, METHODS OF MAKING THE SUBSTRATES, AND METHODS OF DETECTING GLYCOSIDASE ACTIVITIES | ENGASE, GBA3, GMDS | KDM4E 1348/4885ALDH1A1 2454/4885GLA 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.