SCHEMBL8763249

SCHEMBL8763249

FC1=C(F)C2(F)C(F)(F)C(F)(F)C3(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C3(F)C2(F)C(F)(F)C1(F)F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4528772 0.90 MEN1 (0.35) MEN1KMT2ATDP1
SCHEMBL1481548 0.69 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL1483933 0.69 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL1483936 0.69 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL7725530 0.67
SCHEMBL274532 0.66
SCHEMBL9755516 0.66
SCHEMBL332651 0.66
SCHEMBL18979331 0.66 MEN1 (0.89) MEN1KMT2ATDP1
Perflunafene SCHEMBL21916758 0.66 MEN1 (0.89) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594707-B1 PREPARATIONS COMPRISING A FLUOROCARBON AND A LIPOPHILIC/FLUOROPHILIC ORGANIC COMPOUND, AND THEIR USES ALLIANCE PHARMA (US) 1997-05-28 EP claimed