SCHEMBL8763536

SCHEMBL8763536

O=C(O)c1cc(O)cc(O)c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA12 O43570 5/20 0.50
CA7 P43166 5/20 0.50
CA9 Q16790 5/20 0.50
CA14 Q9ULX7 5/20 0.50
ALDH1A1 P00352 4/20 0.50
PTGS2 P35354 3/20 0.50
TSHR P16473 2/20 0.50
ALOX5 P09917 1/20 0.50
CYP3A4 P08684 3/20 0.42
AKR1C4 P17516 2/20 0.42
AKR1C3 P42330 2/20 0.42
AKR1C2 P52895 2/20 0.42
AKR1C1 Q04828 2/20 0.42
ACHE P22303 1/20 0.42
HSD17B10 Q99714 3/20 0.39
HCAR1 Q9BXC0 1/20 0.39
HPGD P15428 4/20 0.38
CA4 P22748 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31233641 0.80 AKR1C3 (0.55) CA1CA2CA12CA7CA9
SCHEMBL21821500 0.80 CA1 (0.54) CA1CA2CA12CA7CA9
SCHEMBL8346094 0.79 TSHR (0.45) CA1CA2CA12CA7CA9
SCHEMBL30863904 0.78 AKR1C2 (0.48) CA1CA2CA12CA7CA9
SCHEMBL566074 0.78 CYP3A4 (0.48) CA1CA2CA12CA7CA9
SCHEMBL31458009 0.78 CA1 (0.42) CA1CA2CA12CA7CA9
SCHEMBL12640833 0.78 KDM4E (0.53) CA1CA2CA12CA7CA9
SCHEMBL29421908 0.76 CA12 (0.60) CA1CA2CA12CA7CA9
SCHEMBL907550 0.76 CA12 (0.60) CA1CA2CA12CA7CA9
SCHEMBL28555327 0.75 CA12 (0.56) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623339-B1 Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation OREAL (FR) 1997-07-23 EP claimed
CN-114805460-B DNA-cholesterol functionalized dendrimer hybrid, and synthetic method and application thereof 温州大学 2023-10-24 CN disclosed
CN-108495563-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2018-09-04 CN disclosed
CN-105612158-B The somatostatin receptor hypotype 5 (SSTR5) antagonist 武田药品工业株式会社 2017-06-30 CN disclosed