Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.56 |
| ▸ | RARB | P10826 | 5/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405705 | 1.00 | TP53 (0.57) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9405707 | 1.00 | TP53 (0.57) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL17848853 | 0.88 | MAPT (0.54) | TP53TSHRPLA2G4BRARBMAPT | |
| SCHEMBL28827576 | 0.87 | NPC1 (0.47) | TP53TSHRPLA2G4BMAPK1 | |
| SCHEMBL2294692 | 0.87 | PRSS1 (0.50) | TSHR | |
| SCHEMBL1900961 | 0.87 | PRSS1 (0.50) | TSHR | |
| SCHEMBL29266799 | 0.87 | PRSS1 (0.50) | TSHR | |
| SCHEMBL2294967 | 0.87 | PRSS1 (0.50) | TSHR | |
| SCHEMBL11699133 | 0.87 | PRSS1 (0.50) | TSHR | |
| SCHEMBL27994629 | 0.87 | PRSS1 (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566379-B1 | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL IND (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5346646-A | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0566379-A2 | Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |