SCHEMBL8764469

SCHEMBL8764469

O=Cc1cc(O)cc(O)c1F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.44
ESR2 Q92731 3/20 0.44
ERN1 O75460 8/20 0.42
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
TYR P14679 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34466630 0.82 ERN1 (0.47) ESR1ESR2ERN1CA12CA1
SCHEMBL17047098 0.78 ERN1 (0.44) ESR1ESR2ERN1TRIM24TRIM33
SCHEMBL19642898 0.78 ERN1 (0.44) ESR1ESR2ERN1TRIM24TRIM33
SCHEMBL14726039 0.78 ERN1 (0.59) ERN1TRIM24TRIM33TYR
SCHEMBL2597207 0.78 ERN1 (0.58) ERN1TRIM24TRIM33TYRCA1
SCHEMBL29459679 0.76 ERN1 (0.50) ESR1ESR2ERN1TRIM24TRIM33
SCHEMBL1003422 0.76 ERN1 (0.50) ESR1ESR2ERN1TRIM24TRIM33
SCHEMBL10118325 0.74 ERN1 (0.42) ESR1ESR2ERN1TRIM24TRIM33
SCHEMBL28611375 0.74 CA9 (0.50) TYRCA12CA1CA9
SCHEMBL3855768 0.74 ERN1 (0.43) ERN1TRIM24TRIM33TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623339-B1 Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation OREAL (FR) 1997-07-23 EP claimed