Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15366239 | 1.00 | MAPT (0.53) | MAPTCNR1CNR2TSHRDGKA | |
| SCHEMBL15366242 | 1.00 | MAPT (0.53) | MAPTCNR1CNR2TSHRDGKA | |
| SCHEMBL1878843 | 0.93 | MAPT (0.56) | MAPTCNR1CNR2TSHRHCAR2 | |
| SCHEMBL9106059 | 0.90 | MAPT (0.54) | MAPTDGKAPPARGPPARAFAAH | |
| SCHEMBL9111129 | 0.90 | MAPT (0.54) | MAPTDGKAPPARGPPARAFAAH | |
| SCHEMBL31404911 | 0.89 | CNR1 (0.58) | MAPTCNR1CNR2DGKAPPARG | |
| SCHEMBL31404901 | 0.87 | CNR1 (0.57) | MAPTCNR1CNR2TSHRDGKA | |
| SCHEMBL7026430 | 0.87 | CNR1 (0.57) | MAPTCNR1CNR2TSHRDGKA | |
| SCHEMBL10783818 | 0.85 | TSHR (0.49) | MAPTTSHRDGKAPPARGPPARA | |
| SCHEMBL7029180 | 0.85 | TSHR (0.49) | MAPTTSHRDGKAPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621257-B1 | Doubly branched compounds and methods of making them | INST FRANCAIS DU PETROLE (FR) | 1997-07-30 | — | — | EP | disclosed |
| US-5434282-A | Alkylation | INSTITUT FRANCAIS DU PETROLE (FR) | 1995-07-18 | — | — | US | disclosed |
| EP-0621257-A1 | Doubly branched compounds and methods of making them | INSTITUT FRANCAIS DU PETROLE (FR) | 1994-10-26 | — | — | EP | disclosed |