Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.69 |
| ▸ | GRM3 | Q14832 | 7/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763631 | 0.88 | GRM2 (0.61) | GRM2GRM3CA1CA2CA9 | |
| SCHEMBL8764439 | 0.87 | GRM2 (0.81) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8764566 | 0.84 | GRM2 (0.77) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8891537 | 0.84 | GRM2 (0.77) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8763970 | 0.84 | GRM2 (0.77) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8763480 | 0.82 | GRM2 (0.61) | GRM2GRM3GRM8GRM4LMNA | |
| SCHEMBL8764708 | 0.82 | GRM2 (1.00) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8764032 | 0.82 | GRM2 (1.00) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8764687 | 0.81 | GRM2 (0.71) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8763907 | 0.79 | GRM2 (0.69) | GRM2GRM3GRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |