Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.65 |
| ▸ | GRM3 | Q14832 | 14/20 | 0.65 |
| ▸ | GRM8 | O00222 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | GRM6 | O15303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892624 | 1.00 | GRM2 (0.65) | GRM2GRM3GRM8GRM4SLC1A2 | |
| SCHEMBL8764458 | 0.92 | GRM2 (0.64) | GRM2GRM3GRM8GRM4SLC1A2 | |
| SCHEMBL8764465 | 0.88 | GRM2 (0.65) | GRM2GRM3GRM8GRM4SLC1A2 | |
| SCHEMBL8764687 | 0.88 | GRM2 (0.71) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8764501 | 0.88 | GRM2 (0.75) | GRM2GRM3GRM8GRM4SLC1A2 | |
| SCHEMBL8891838 | 0.86 | GRM2 (0.63) | GRM2GRM3GRM8GRM4SLC1A2 | |
| SCHEMBL8762579 | 0.86 | GRM2 (0.63) | GRM2GRM3GRM8GRM4SLC1A2 | |
| SCHEMBL8763907 | 0.86 | GRM2 (0.69) | GRM2GRM3GRM8GRM4SLC1A2 | |
| SCHEMBL8764755 | 0.86 | GRM2 (0.60) | GRM2GRM3GRM8GRM4 | |
| SCHEMBL8763480 | 0.85 | GRM2 (0.61) | GRM2GRM3GRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |