Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053042 | 0.89 | PRNP (0.52) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7449784 | 0.77 | PRNP (0.54) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7049715 | 0.74 | PRNP (0.46) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8764856 | 0.72 | PRNP (0.53) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7049726 | 0.72 | PRNP (0.50) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7050341 | 0.71 | CYP3A4 (0.39) | ALDH1A1MAPTKDM4ELMNANPC1 | |
| SCHEMBL8764852 | 0.71 | PRNP (0.57) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL9067056 | 0.70 | PRNP (0.53) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7049709 | 0.69 | PRNP (0.52) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8764771 | 0.69 | PRNP (0.49) | PRNPKMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-B1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1997-07-16 | — | — | EP | disclosed |