Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | SHBG | P04278 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764823 | 1.00 | SRD5A2 (0.53) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8764208 | 0.86 | SRD5A2 (0.49) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8764199 | 0.86 | SRD5A2 (0.49) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8765019 | 0.85 | SRD5A2 (0.52) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8765020 | 0.85 | SRD5A2 (0.52) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8765548 | 0.85 | SRD5A2 (0.48) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8765555 | 0.85 | SRD5A2 (0.48) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7614985 | 0.72 | PSEN1 (0.80) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7614986 | 0.72 | PSEN1 (0.80) | SRD5A2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5907025 | 0.72 | PSEN1 (0.80) | SRD5A2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785943-A1 | SYNTHESIS OF 6-AZAANDROSTENONES | GLAXO WELLCOME INC. (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5541322-A | Synthesis of 6-azaandrostenones | GLAXO WELLCOME INC. (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1996011939-A1 | SYNTHESIS OF 6-AZAANDROSTENONES | GLAXO WELLCOME INC. (US) | 1996-04-25 | — | — | WO | disclosed |