Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Formic Acid Methyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid Methyl Ester SCHEMBL1330535 | 0.95 | — | — | |
| Formic Acid Methyl Ester SCHEMBL1332784 | 0.95 | — | — | |
| Formic Acid Methyl Ester SCHEMBL650 | 0.95 | — | — | |
| Formic Acid Methyl Ester SCHEMBL935999 | 0.95 | — | — | |
| Formic Acid Methyl Ester SCHEMBL8027094 | 0.90 | — | — | |
| Formic Acid Methyl Ester SCHEMBL11552131 | 0.90 | — | — | |
| Formic Acid Methyl Ester SCHEMBL14787285 | 0.90 | TDP1 (0.35) | — | |
| Formic Acid Methyl Ester SCHEMBL5911172 | 0.90 | — | — | |
| Formic Acid Methyl Ester SCHEMBL7925276 | 0.90 | — | — | |
| Formic Acid Methyl Ester SCHEMBL10773235 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946641-A | A kind of method for preparing trans diphenylethlene class compound | 浙江大学 | 2017-07-14 | — | — | CN | disclosed |
| EP-0784628-A1 | INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | Vertex Pharmaceuticals Incorporated (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1995035308-A1 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1995-12-28 | — | — | WO | disclosed |