Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876492 | 1.00 | NPC1 (0.31) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL876493 | 1.00 | NPC1 (0.31) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL876511 | 0.99 | NPC1 (0.33) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL876510 | 0.99 | NPC1 (0.33) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL876509 | 0.99 | NPC1 (0.33) | NPC1RAB9ACNR1CNR2 | |
| SCHEMBL875245 | 0.99 | — | — | |
| SCHEMBL875246 | 0.99 | — | — | |
| SCHEMBL875244 | 0.99 | — | — | |
| SCHEMBL872102 | 0.97 | CHRM1 (0.31) | — | |
| SCHEMBL872101 | 0.97 | CHRM1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619189-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038851-A1 | ISOXAZOLINE OXIMES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-03-29 | — | — | WO | disclosed |