Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 7/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.54 |
| ▸ | HSD17B7 | P56937 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765326 | 1.00 | SRD5A1 (0.55) | SRD5A1SRD5A2HSD17B7 | |
| SCHEMBL8542155 | 0.91 | SRD5A1 (0.49) | SRD5A1SRD5A2HSD17B7 | |
| SCHEMBL8542153 | 0.91 | SRD5A1 (0.49) | SRD5A1SRD5A2HSD17B7 | |
| SCHEMBL9114790 | 0.90 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8541811 | 0.90 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL9114783 | 0.90 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8541816 | 0.90 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL9283627 | 0.89 | SRD5A1 (0.48) | SRD5A1SRD5A2HSD17B7 | |
| SCHEMBL8539912 | 0.89 | SRD5A1 (0.48) | SRD5A1SRD5A2HSD17B7 | |
| SCHEMBL9283632 | 0.89 | SRD5A1 (0.48) | SRD5A1SRD5A2HSD17B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646007-B1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONES AS 5$g(a)-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1997-08-13 | — | — | EP | claimed |
| EP-0646007-B1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONES AS 5$g(a)-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1997-08-13 | — | — | EP | disclosed |