SCHEMBL8765464

SCHEMBL8765464

C=CCC(C)OC(=O)/C=C\C(=O)OC(C)CC=C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.43
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPT P10636 2/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
CA12 O43570 1/20 0.31
AKR1B10 O60218 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
AKR1B1 P15121 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
CHRNB2 P17787 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765468 0.92 HCAR2 (0.57) HCAR2TSHRALDH1A1MAPTTDP1
SCHEMBL8765477 0.92 HCAR2 (0.57) HCAR2TSHRALDH1A1MAPTTDP1
SCHEMBL9246267 0.82 TSHR (0.35) TSHRALDH1A1LMNAMAPTGRIK1
SCHEMBL766965 0.82 TSHR (0.35) TSHRALDH1A1LMNAMAPTGRIK1
SCHEMBL766966 0.80
SCHEMBL6291341 0.80
SCHEMBL9541746 0.80
SCHEMBL19418189 0.80
SCHEMBL25019357 0.79 KMT2A (0.55) HCAR2ALDH1A1LMNAMAPTCA12
SCHEMBL28671566 0.79 KMT2A (0.55) HCAR2ALDH1A1LMNAMAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US claimed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP claimed
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
US-5554695-A Styrenic copolymer and process for producing same IDEMITSU KOSAN CO. LTD. (JP) 1996-09-10 US disclosed
EP-0511407-B1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN CO (JP) 1996-05-29 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5475061-A High degree of syndiotactic configuration; using alumoxane and transition metal compound catalysts IDEMITSU KOSAN CO., LTD. (JP) 1995-12-12 US disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP disclosed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US disclosed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP disclosed