SCHEMBL8765607

SCHEMBL8765607

CCOc1ccc([Si](C)(C)[K])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.61
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PARP10 Q53GL7 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
LTA4H P09960 2/20 0.47
ADRA2A P08913 2/20 0.46
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
HPGD P15428 2/20 0.44
RAB9A P51151 2/20 0.44
TP53 P04637 1/20 0.44
HSD17B10 Q99714 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277365 0.82 NQO1 (0.67) NQO1TSHRTDP1PARP10PRSS1
SCHEMBL9668699 0.78 NQO1 (0.61) NQO1TSHRTDP1PARP10PRSS1
SCHEMBL3625601 0.78 NQO1 (0.61) NQO1TSHRTDP1PARP10PRSS1
SCHEMBL8618122 0.78 NQO1 (0.61) NQO1TSHRTDP1PARP10PRSS1
SCHEMBL10351802 0.78 NQO1 (0.61) NQO1TSHRTDP1PARP10PRSS1
SCHEMBL8143365 0.78 NQO1 (0.61) NQO1TSHRTDP1PARP10PRSS1
SCHEMBL9292576 0.78 NQO1 (0.61) NQO1TSHRTDP1PARP10PRSS1
1,4-Diethoxybenzene SCHEMBL124015 0.78 NQO1 (1.00) NQO1TSHRTDP1PARP10PRSS1
1,4-Diethoxybenzene SCHEMBL28186701 0.78 NQO1 (1.00) NQO1TSHRTDP1PARP10PRSS1
SCHEMBL10588253 0.77 NQO1 (0.67) NQO1TSHRTDP1PARP10PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed