Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665036 | 0.91 | TSHR (0.65) | KMT2ATSHRSMPD1PLA2G4BGGPS1 | |
| SCHEMBL8766568 | 0.91 | TSHR (0.65) | KMT2ATSHRSMPD1PLA2G4BGGPS1 | |
| SCHEMBL2089702 | 0.91 | TSHR (0.65) | KMT2ATSHRSMPD1PLA2G4BGGPS1 | |
| SCHEMBL9717879 | 0.91 | TSHR (0.65) | KMT2ATSHRSMPD1PLA2G4BGGPS1 | |
| SCHEMBL7297045 | 0.89 | TSHR (0.62) | KMT2ATSHRSMPD1PLA2G4BGGPS1 | |
| SCHEMBL1805409 | 0.84 | TSHR (0.54) | KMT2ATSHRSMPD1CYP1A2CYP2C19 | |
| SCHEMBL8766476 | 0.83 | KMT2A (0.54) | KMT2ATSHRKDM4EALDH1A1CYP2D6 | |
| SCHEMBL8765694 | 0.82 | KMT2A (0.61) | KMT2ATSHRSMPD1KDM4EALDH1A1 | |
| SCHEMBL14384339 | 0.82 | PLA2G4B (0.70) | KMT2ATSHRSMPD1POLBPLA2G4B | |
| SCHEMBL14383496 | 0.81 | PLA2G4B (0.69) | KMT2ATSHRSMPD1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |