Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.50 |
| ▸ | RARG | P13631 | 7/20 | 0.50 |
| ▸ | RARA | P10276 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | GOT1 | P17174 | 1/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766169 | 0.89 | RARB (0.54) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8765824 | 0.86 | RARG (0.67) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9078763 | 0.85 | RARB (0.50) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8766427 | 0.84 | RARG (0.61) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9078576 | 0.83 | RARB (0.68) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8766471 | 0.83 | RARB (0.55) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9079143 | 0.81 | RARB (0.50) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8766335 | 0.81 | RARB (0.57) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7929993 | 0.81 | MEN1 (0.51) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8765849 | 0.81 | RARB (0.49) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584191-B1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | CIRD GALDERMA (FR) | 1997-08-13 | — | — | EP | claimed |
| US-5547983-A | Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1996-08-20 | — | — | US | disclosed |