Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766005 | 1.00 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8766002 | 1.00 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8544437 | 0.88 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8544435 | 0.88 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8542309 | 0.85 | SRD5A1 (0.54) | SRD5A1SRD5A2 | |
| SCHEMBL8542306 | 0.85 | SRD5A1 (0.54) | SRD5A1SRD5A2 | |
| SCHEMBL8539919 | 0.84 | SRD5A1 (0.50) | SRD5A1SRD5A2 | |
| SCHEMBL8539921 | 0.84 | SRD5A1 (0.50) | SRD5A1SRD5A2 | |
| SCHEMBL8539920 | 0.84 | SRD5A1 (0.50) | SRD5A1SRD5A2 | |
| SCHEMBL8542159 | 0.81 | SRD5A1 (0.59) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646007-B1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17$g(b)-SUBSTITUTED-4-AZA-5$g(a)-ANDROSTAN-3-ONES AS 5$g(a)-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1997-08-13 | — | — | EP | claimed |
| WO-1993023050-A1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |