Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765060 | 0.81 | MAPK1 (0.55) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| SCHEMBL28682767 | 0.81 | MAPK1 (0.67) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| SCHEMBL9244855 | 0.80 | MAPK1 (0.59) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| SCHEMBL27506519 | 0.79 | MAPK1 (1.00) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| SCHEMBL8939342 | 0.79 | MAPK1 (1.00) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| Benzene SCHEMBL25312146 | 0.79 | MAPK1 (1.00) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| SCHEMBL15450 | 0.79 | MAPK1 (1.00) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| Propane SCHEMBL481265 | 0.78 | MAPK1 (0.85) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| SCHEMBL12599027 | 0.78 | MAPK1 (0.61) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 | |
| SCHEMBL11222460 | 0.78 | MAPK1 (0.61) | MAPK1ALDH1A1ALOX15TAAR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785964-A1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | THE DOW CHEMICAL COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011970-A1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | THE DOW CHEMICAL COMPANY (US) | 1996-04-25 | — | — | WO | disclosed |