SCHEMBL8766321

SCHEMBL8766321

OCC1(COCc2ccccc2)COC(c2ccccc2)OC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
KCNA4 P22459 1/20 0.38
KCNA1 Q09470 1/20 0.38
KCNAB1 Q14722 1/20 0.38
TACR1 P25103 1/20 0.37
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
GRM5 P41594 1/20 0.35
GRIN1 Q05586 1/20 0.34
GRIN2B Q13224 1/20 0.34
SOAT1 P35610 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC6A2 P23975 1/20 0.33
PDE4D Q08499 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10085150 0.90 MEN1 (0.53) MEN1CYP2C19KMT2AALDH1A1TSHR
SCHEMBL9274987 0.82 TSHR (0.45) MEN1KMT2ATSHRTACR1KDM4E
SCHEMBL744431 0.82 MEN1 (0.62) MEN1CYP2C19KMT2AALDH1A1TSHR
SCHEMBL15033001 0.81 MEN1 (0.44) MEN1CYP2C19KMT2AALDH1A1KCNA4
SCHEMBL13241588 0.77 MEN1 (0.43) MEN1CYP2C19KMT2AALDH1A1TSHR
SCHEMBL16130837 0.77 MEN1 (0.43) MEN1CYP2C19KMT2ATSHRKCNA4
SCHEMBL13241591 0.77 CYP2C19 (0.40) MEN1CYP2C19KMT2AALDH1A1TSHR
SCHEMBL3488328 0.77 TSHR (0.50) TSHRTACR1KDM4EPOLBGRM5
SCHEMBL4812907 0.76 MEN1 (0.55) MEN1CYP2C19KMT2AALDH1A1KCNA4
SCHEMBL10085151 0.75 MEN1 (0.53) MEN1CYP2C19KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0485614-B1 CYCLODEXTRIN DERIVATIVE TOPPAN PRINTING CO LTD (JP) 1997-08-13 EP disclosed
US-5241059-A Highly water soluble TOPPAN PRINTING CO., LTD. (JP) 1993-08-31 US disclosed
EP-0485614-A1 CYCLODEXTRIN DERIVATIVE Toppan Printing Co., Ltd. (JP) 1992-05-20 EP disclosed